Papers

This PhD dissertation is based upon the following three papers:

• Paper 1 Existing fluid responsiveness studies using the mini-fluid challenge may be misleading: Methodological considerations and simulations. Published in Acta Anaesthesiologica Scandinavica, 2021. DOI: 10.1111/aas.13965.
• Paper 2 Using generalized additive models to decompose time series and waveforms, and dissect heart–lung interaction physiology. Published in Journal of Clinical Monitoring and Computing, 2022. DOI: 10.1007/s10877-022-00873-7.
• Paper 3 The Effects of Respiratory Rate and Tidal Volume on Pulse Pressure Variation in Healthy Lungs—A Generalized Additive Model Approach May Help Overcome Limitations. Submitted for publication.